Tirzepatide to Retatrutide: The Ultimate Transition Guide (Dosing & Protocols)

The Hunter Williams Podcast - En podcast av Hunter Williams

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Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Are you thinking about switching from tirzepatide to retatrutide? In this video, I’ll walk you through everything you need to know about making the transition—from the science and mechanisms, to real-world dosing strategies and the side effect differences I see in my community. If you’re looking for maximum fat loss and the most up-to-date peptide protocols, this video is for you.Timestamps0:00 – Introduction: Why the switch from tirzepatide to retatrutide is happening0:45 – Clinical background: Compounding issues and the rising popularity of retatrutide1:30 – My transition philosophy: Gradual tapering and best practices2:04 – Mechanisms: How tirzepatide and retatrutide work in the body3:10 – Tirzepatide: GIP and GLP-1 agonism explained3:54 – Why tirzepatide has fewer side effects vs semaglutide4:01 – Retatrutide: What does triple agonism mean?4:42 – Metabolic advantages: Glucagon receptor activation, liver fat reduction, energy expenditure5:45 – Head-to-head comparison: Why retatrutide is stronger for fat loss6:51 – Dose escalation: How to titrate both drugs (side effects & protocol)7:56 – Study outcomes: Average weight loss on both drugs9:10 – A1C improvements: Comparing metabolic health markers10:00 – Retatrutide’s liver benefits and impact on longevity11:02 – What to expect when you switch: Side effects, hunger, and adaptation12:02 – Appetite differences: Why tirzepatide suppresses appetite more at equal doses13:30 – Side effect management: GI symptoms, heart rate, and tips14:02 – My detailed titration schedule for switching safely16:50 – Can you mix tirzepatide and retatrutide?17:39 – Why minimum effective dosing matters and other fat loss pathways18:01 – Final thoughts: Community support, feedback, and closingIn this video you’ll learn: • The step-by-step protocol to taper down tirzepatide and introduce retatrutide safely • Key differences in mechanisms (GIP/GLP-1 vs GIP/GLP-1/Glucagon) • Real world data on weight loss, A1C, and fatty liver reduction • My honest recommendations for side effect management • How to listen to your body and titrate up for maximum effect • Answers to common questions: can you combine both, and is the switch right for you?

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